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RSGOALS · RS3

Biohazard Requirements & Quick Guide

NoviceMembersElf (Prifddinas) series3 QPReleased 23 October 2002

Everything you need before starting Biohazard in RuneScape 3: skill levels, the full chain of quests to finish first, and what completing it opens up. Check your own stats against it below.

Requirements from the RuneScape Wiki (CC BY-NC-SA 3.0), snapshot 2026-09-28.

Skill requirements

Check my stats

Enter your RuneScape name to compare your hiscores levels with every requirement below. Unranked skills read as level 1.

Biohazard itself

No skill requirements for Biohazard itself.

Quest requirements

1 direct prerequisite, 1 quest in the full chain. The tree shows each quest's own requirements beneath it.

Quick guide: order to unlock Biohazard

One valid order: every quest comes after its own prerequisites. Skip any you have already done.

  1. Plague City
  2. Biohazard

Ironman notes

High Ironman priority (8/10 in our Ironman ranking).

See where it fits in the Ironman Quest Cape order.

XP rewards

Skills Biohazard gives guaranteed XP in (fixed XP or a skill-locked lamp; choice lamps not listed). See the wiki for exact amounts.

  • ThievingThieving

Quests that need Biohazard

Full walkthrough, items needed and exact rewards: Biohazard on the RuneScape Wiki . Requirement data is adapted from the wiki under CC BY-NC-SA 3.0.

All RS3 quests · Quest Cape order for Ironmen · XP calculator